Abstract

Clinico-pathological and molecular based investigation of PPR virus in goats

Authors: Muhammad Moazzam Jalees, Hafiz Muhammad Ishaq, Abu Baker Siddique, Muhammad Fakhar-e-Alam Kulyar, Samina Shabbir, Prerona Boruah, Wangyuan Yao and Zeeshan Ahmad Bhutta

DOI: http://dx.doi.org/10.71081/cvj/2022.012

Abstract
Peste des petits ruminants (PPR) is a deadly viral illness that affects small ruminants, especially goats. The Peste des petits affects both small and big ruminants and is a highly contagious illness. The disease is extremely infectious and has a fluctuating risk of recurrence in Punjab, Pakistan, with a reported fatality rate of 35-60%, the disease is of enormous economic importance and prevalent throughout Asia. After a PPR epidemic in Pakistan's Bahawalpur area, the current study was undertaken on a private farm. The goats were categorized into different groups based on breed age and sex during the investigation. Different breeds had greater rates of morbidity, death, and case fatality than non-descriptive animals. Morbid animals showed characteristic clinical signs and symptoms of PPR. The morbidity, mortality and case fatality were very high. Different characteristic clinical signs and postmortem lesions were observed in PPR infected animals. At microscopic level, various microscopic lesions in heart, kidneys, lungs, liver, spleen, and intestine were observed. The results of this study suggested that frequent and regular investigation of PPR infection is vital to control and limit the spread of viruses and implement suitable control plans to lower the risks of viruses in small ruminants.

Keywords: Goats, Clinical signs, Necropsy lesions, Histopathology, PCR