Abstract

Deciphering the Consequences of Purposeful Triamcinolone Administration on Quail Blood Composition and Biochemical Markers

Authors: Saima Noreen, Ayesha Ghani, Sidra Muhyuddin, Tabinda Afzal, Saima Riaz, Komal Arshad, Asma Malik, Mah Noor, Zubair Azhar Nomi, Mahnoor Malik, Nimra and Hamid Zafar

DOI: http://dx.doi.org/10.71081/cvj/2024.022

Abstract
Triamcinolone is a commonly used man-made glucocorticoid which influences a broad spectrum of bodily functions and processes. Research in hematology and serum biochemistry can provide valuable data on an individual's physical condition to make them a useful tool to differentiate healthy birds from affected birds. Hematological parameters such as Red blood cells (RBCs) , White blood cells (WBCs), average cell size (Mean Cell Volume), hemoglobin levels and clinical biochemistry were observed in this analysis. Total 120 birds were purchased from the market. A total of 60 birds were used in winter and 60 in spring trial. All the birds were divided into three groups one kept as control, second group was given low concentration (0.02mL/mg) of triamcinilone and third group received high concentration (0.04mL/mg) of triamcinilone. The medical symptoms were noted as anxiety, vomiting and swelling on spleen and knees although lethargy in all treatment groups except control. Analysis of data reveals that decline in RBCs were significant (P<0.05) while enhancement in WBCs occured. Overall, the impact of steroids on the serum biochemistry profile suggests significant damage to vital organs including increased level of cholesterol and uric acid in the liver and kidney. The findings emphasize that triamcinolone administration poses significant health risks in birds, particularly affecting vital organ function. This study underscores the need for careful consideration of dosage and potential side effects when using glucocorticoids in avian species. Furhermore, these findings help to assess the effects of triamcinolone on serum biochemistry profiles (liver and kidney function, cholesterol, uric acid) and identify the potential risks of health associated with triamcinolone administration in bird.

Keywords: Alanine Amino Transferase, Aspartate Amino Transferase (AAT), Hemoglobin, Mean Cell Volume (MCV), Mean Corpuscular, Hemoglobin (MCH), Triamcinolone.