Abstract

Antibiotic Resistance Profiles of Lactobacillus spp. from Animal and Food Ecosystems

Authors: Muhammad Taha, Afaf Jauhar and Muhammad Muneeb

DOI: http://dx.doi.org/10.71081/cvj/2025.053

Abstract
Numerous ARGs in Lactobacillus species are linked with mobile genetic elements, indicating the possibility of horizontal gene transfer to other beneficial and pathogenic microorganisms in the food chain and gastrointestinal tract. Acquired resistance poses a serious risk for the spread of ARGs, but intrinsic resistance in Lactobacillus (such as to vancomycin and aminoglycosides) is typically regarded as non-transferable and of low safety concern. Because Lactobacillus strains are widely used in food and probiotic compositions, strain selection should incorporate thorough safety evaluation, including phenotypic and molecular AR profiling, before commercialization. To prevent the emergence of resistance and protect public health and food safety, it is crucial to continuously monitor AR trends in animal and food-associated Lactobacillus spp.

Keywords: Acquired resistance; Antibiotic resistance; Antibiotic resistance genes (ARGs)