Abstract

Antibacterial Potential of Honeybee (Apis mellifera) Venom against Pseudomonas aeruginosa

Authors: Mukarma Mahmood, Muhammad Moazam Jalees, Muhammad Waseem Abbas, Waqas Ashraf, Abdullah Saghir Ahmad, Zeeshan Nawaz, Qudratullah, Shah Nawaz and Roshan Riaz

DOI: http://dx.doi.org/10.71081/cvj/2026.067

Abstract
The study investigated the antibacterial properties of honeybee venom against P. aeruginosa. Honeybee venom contains antibacterial compounds that can help to treat lung and urinary tract infections caused by the Gram-negative bacterium P. aeruginosa. A study involving 264 clinical samples from urine, sputum, and pus found that venom had potent antibacterial properties against P. aeruginosa. The study found that venom preparation techniques could affect antibiotic efficacy and warranted further research. The most common source of samples was pus, and wound infections, abscesses, and post-operative infections were common diagnoses. When PCR was done, a particular primer was found. A distinct band on the gel at 396 and 1600 base pairs (bp) indicates the expected size of the amplicon for the Exo A and 16S rRNA genes. The study suggests that venom can be used in combination with other drugs to combat P. aeruginosa and could be beneficial for treating infections caused by bacterial activity.

Keywords: Antimicrobial activity, Apis mellifera, Bee venom, MIC, Pseudomonas aeruginosa, Zone of inhibition